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99.2% On-Time Delivery

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Refund within 28 days

Refund Within 28 Days

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99% Purity guarantee

Each peptide batch is tested and verified to meet or exceed 98–99% purity (HPLC).

Storage Handling Notice

Store 2–8 °C (≤–20 °C long-term). RT exposure during transport acceptable. Protect from light.

Licensed partner pharmacies

99.2% On-Time Delivery

Tracked international shipping

Tracked International Shipping

Refund within 28 days

Refund Within 28 Days

Secure, encrypted checkout

Secure, Encrypted Checkout

HCG (5000iu)

$40.00

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This product is available by prescription only

This product does not require a prescription

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99% Purity guarantee

Each peptide batch is tested and verified to meet or exceed 98–99% purity (HPLC).

Storage Handling Notice

Store 2–8 °C (≤–20 °C long-term). RT exposure during transport acceptable. Protect from light.

Product Form

The product is delivered in powdered (lyophilized) form and must be properly reconstituted prior to research use.

Direct LH Receptor Agonist Profile

HCG is a glycoprotein hormone structurally analogous to endogenous luteinizing hormone, binding LH receptors on Leydig cells to initiate receptor-mediated intracellular signaling cascades in experimental models. Unlike upstream HPG axis modulators operating through hypothalamic or pituitary intermediaries, HCG enables investigation of LH receptor-specific signaling behavior in isolation from upstream regulatory variables. This direct receptor engagement profile supports mechanistic characterization of LH receptor occupancy kinetics, downstream cAMP-mediated signaling cascade dynamics, and receptor-linked molecular marker activity in preclinical Leydig cell experimental systems.

Gonadotropin Receptor Signaling Research

HCG supports investigation of gonadotropin receptor-mediated signaling dynamics across testicular and ovarian tissue experimental models. Research applications include characterization of LH receptor interaction behavior, receptor sensitivity parameters, and downstream intracellular signaling pathway marker expression under defined experimental exposure conditions. Comparative study designs employing HCG alongside upstream HPG axis modulators enable systematic molecular endpoint differentiation between direct LH receptor agonism and GnRH-mediated gonadotropin release pathway signaling dynamics.

USA GMP-Certified Supply via Novera

Novera supplies HCG 5000iu sourced from USA GMP-certified manufacturing facilities, independently verified to approximately 99% purity by third-party COA documentation. Each vial confirms glycoprotein hormone sequence identity, purity grade, and batch-specific quality control data — providing research laboratories with consistent, pharmaceutical-grade LH receptor agonist material for advanced gonadotropin receptor interaction and signal transduction research.

HCG 5000iu is suited for research teams and reproductive endocrinology laboratories investigating LH receptor interaction dynamics, receptor occupancy parameters, and downstream intracellular signaling pathway marker characterization in controlled preclinical models. Scientists examining LH receptor binding affinity, cAMP-mediated signal transduction dynamics, and receptor-specific molecular endpoint behavior in Leydig cell experimental systems will find HCG relevant to mechanistic gonadotropin receptor pharmacology study designs.

Research programs requiring a structurally defined direct LH receptor agonist reference compound for comparative receptor pharmacology investigations alongside upstream HPG axis modulators such as Kisspeptin or Gonadorelin benefit from HCG’s distinct receptor-level activation profile. Laboratories studying gonadotropin receptor signaling behavior, receptor sensitivity dynamics, and pathway-level molecular differentiation in reproductive tissue experimental models will find HCG well-suited to multi-arm gonadotropin signaling research designs. Novera supplies HCG 5000iu sourced from USA GMP-certified manufacturing facilities, with each vial COA-verified for purity and potency to approximately 99%.

Leydig Cell LH Receptor Binding Kinetics and Signal Transduction Studies

HCG supports in vitro and ex vivo investigation of LH receptor occupancy dynamics, receptor binding affinity parameters, and downstream intracellular signaling cascade activation in Leydig cell experimental models. Researchers characterizing cAMP second messenger pathway activity and receptor-linked molecular marker dynamics following direct LH receptor engagement use HCG as a reference compound for mechanistic gonadotropin receptor pharmacology study designs.

Downstream Intracellular Signaling Cascade Characterization

Laboratories studying LH receptor-mediated signal transduction use HCG to quantify downstream intracellular molecular marker activity, second messenger signaling cascade dynamics, and receptor-linked pathway behavior in controlled preclinical Leydig cell model systems. Multi-arm protocols comparing direct LH receptor agonist and upstream GnRH-mediated gonadotropin release downstream signaling profiles support mechanistic characterization of pathway-specific molecular endpoint differentiation.

Comparative Direct LH Receptor Agonism vs. Upstream HPG Axis Modulator Studies

HCG’s direct LH receptor activation profile enables multi-arm comparative study designs examining how direct gonadotropin receptor agonism produces distinct downstream intracellular signaling pathway marker patterns relative to upstream HPG axis modulators such as Kisspeptin or Gonadorelin. Research quantifying molecular endpoint differences between direct receptor engagement and upstream pathway modulation contributes to mechanistic understanding of gonadotropin signaling biology in preclinical models.

Preparation Guidelines

Reconstitute lyophilized HCG 5000iu with sterile bacteriostatic water using standard sterile laboratory technique. Reconstitution volume should be determined based on the target experimental working concentration specified by the study design. Research protocols examining LH receptor sensitivity dynamics and steroidogenic pathway marker progression typically employ defined administration intervals with systematic endpoint monitoring; document each reconstitution step in accordance with institutional research record-keeping standards. Use calibrated laboratory equipment throughout all preparation steps.

Storage Conditions

Store lyophilized glycoprotein hormone at 2–8°C, protected from light and moisture, prior to reconstitution. Following reconstitution, maintain strict refrigeration at 2–8°C; reconstituted hormone remains stable for use within the timeframe specified in accompanying experimental documentation. This product does not require cold-chain shipping, but immediate refrigeration upon receipt is recommended to preserve glycoprotein hormone structural integrity and biological activity throughout the protocol period. Each vial supplied by Novera includes COA documentation and handling guidance.

Protocol Duration Guidelines

Preclinical reproductive endocrinology studies using HCG span a broad range depending on experimental objectives — from short-term acute LH receptor activation and binding kinetics investigations through extended multi-week steroidogenic pathway marker progression and receptor sensitivity characterization protocols. Initial measurable downstream Leydig cell signaling marker responses in preclinical models may be observed within days of administration. Monitor LH receptor pathway activity markers, downstream steroidogenic enzyme expression dynamics, gonadotropin-dependent reproductive pathway markers, and receptor sensitivity indicators at defined experimental intervals throughout the observation period, in accordance with institutional laboratory standards.

  • CAS: 9002-61-3
  • Chemical Formula: C₁₁₀₅H₁₇₇₀N₃₁₈O₃₃₆S₂₆
  • Molecular Weight: ~36.7 kDa (37,000 Da)
  • Synonyms: Human Chorionic Gonadotropin, Chorionic gonadotropin, Choriogonin, Endocrine, Gonabion
  • Shelf life: 24 months from the manufacturing date.

Why Choose Novera Research Peptides?

Novera Research delivers high-quality research peptides developed under strict manufacturing and quality-control standards. Each product is carefully synthesized, tested, and handled to ensure consistency, reliability, and transparency for advanced research applications.

High-purity, research-grade peptide synthesis

Analytical testing to verify quality and composition

Consistent batch-to-batch performance

Batch identification on every vial for traceability

Stored and shipped under controlled conditions

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Order HCG (5000iu)
Reliable Research-Grade HCG (5000iu) Peptide with Verified Laboratory Quality
HCG 5000iu from Novera provides research teams with a COA-verified, USA GMP-sourced pharmaceutical-grade LH receptor agonist glycoprotein for preclinical gonadotropin receptor pharmacology, Leydig cell steroidogenic signaling pathway marker characterization, and comparative direct LH agonist vs. upstream HPG axis modulator molecular endpoint studies. Each vial delivers consistently characterized glycoprotein hormone material to approximately 99% purity with full batch documentation. Global secure shipping is available for laboratory orders. Every order includes COA documentation, handling instructions, and access to technical support for multi-arm gonadotropin receptor signaling experimental protocol design.

Frequently Asked Questions

How does HCG's receptor activation mechanism differ from upstream HPG axis modulators in research models?
What administration interval parameters are typically employed in preclinical LH receptor signaling research?
Can HCG be employed in long-term preclinical reproductive endocrinology protocols?